古希腊的肝病仙药
华盛顿州贝斯特耳大学的约瑟夫皮佐诺声称：“奶蓟可能是目前已知最有效的肝脏保护剂。”
临床应用
治疗毒蕈中毒
Ward, Jeanine, et al. "Amatoxin poisoning: case reports and review of current therapies." The Journal of emergency medicine 44.1 (2013): 116-121.
辅助治疗肝硬化及慢性肝病
Federico, Alessandro, Marcello Dallio, and Carmelina Loguercio. "Silymarin/silybin and chronic liver disease: a marriage of many years." Molecules 22.2 (2017): 191.
对抗肝癌
Polachi, Navaneethakrishnan, et al. "Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer–A comprehensive review." European journal of medicinal chemistry 123 (2016): 577-595.
保护肝细胞
Vargas-Mendoza, Nancy, et al. "Hepatoprotective effect of silymarin." World journal of hepatology 6.3 (2014): 144.
改善各种程度的失智症
Kumar, Amit, et al. "Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia." Naunyn-Schmiedeberg's archives of pharmacology 387.8 (2014): 777-787.
辅助治疗神经退化症
Pérez-Hernández, Jesús, et al. "A potential alternative against neurodegenerative diseases: Phytodrugs." Oxidative medicine and cellular longevity 2016 (2016).
预防更年期骨质疏松症
Kim, Jung-Lye, et al. "Antiosteoclastic activity of milk thistle extract after ovariectomy to suppress estrogen deficiency-induced osteoporosis." BioMed research international 2013 (2013).
改善痤疮
Sahib, A. S., et al. "Effects of oral antioxidant lesion counts associated with oxidative stress and inflammation in patients with papulopustular acne." J Clin Exp Dermatol Res 3.5 (2012): 1-6.
有助于改善糖尿病
Voroneanu, Luminita, et al. "Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials." Journal of diabetes research 2016 (2016).
减轻放化疗的副作用
Bosch-Barrera, Joaquim, Bernardo Queralt, and Javier A. Menendez. "Targeting STAT3 with silibinin to improve cancer therapeutics." Cancer treatment reviews 58 (2017): 61-69.
有助于防治前列腺癌
Davis-Searles, Paula R., et al. "Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells." Cancer research 65.10 (2005): 4448-4457.
你知道吗？
奶蓟的茎和叶片被切开时会流出乳白色的组织液，故名“奶汁树“。1968年有科学家从乳蓟中提炼出三种有护肝作用的黄酮素，统称为水飞蓟，水飞蓟有强大的抗氧化力，能增加肝脏内谷胱甘肽的含量。
Q&A
奶蓟可以和西药同服吗？
由于奶蓟对肝脏的作用显著，因此某些与P450酵素系统作用有关的药物，如阿米替林(Elavil)、安定(Valium)、齐留通(Zyflo)、赛来昔布(Celebrex)、双氯芬酸(Voltaren)、氟伐他汀(Lescol)、格列吡嗪(Glucotrol)、布洛芬(Advil)、厄贝沙坦(Avapro)、洛沙坦(Cozaar)、苯妥英(Dilantin)、吡罗昔康(Feldene)、三苯氧胺(Nolvadex)、甲糖宁(Tolinase)、托拉塞米(Demadex)、华法林(Coumadin)等都不适合同服。