蕈类β葡聚糖

免疫细胞最爱的营养素

经过多年的研究，蕈类β葡聚糖已经被科学家认定为“生物反应调节剂”，可以直接或间接地增强机体来对抗肿瘤。

• Novak, M., and V. Vetvicka. "Glucans as biological response modifiers." Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders) 9.1 (2009): 67-75.

临床应用

强化T细胞、B细胞、自然杀手细胞、吞噬细胞和树突细胞

• Chan, Godfrey Chi-Fung, Wing Keung Chan, and Daniel Man-Yuen Sze. "The effects of β-glucan on human immune and cancer cells." Journal of hematology & oncology 2.1 (2009): 25.

能够刺激神经生长因子，治疗四肢神经损伤

• Wong, Kah-Hui, et al. "Neuroregenerative potential of lion's mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers.(higher Basidiomycetes), in the treatment of peripheral nerve injury." International journal of medicinal mushrooms 14.5 (2012).

具有抗疲劳作用

• Liu, Jianqing, et al. "Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus." Experimental and therapeutic medicine 9.2 (2015): 483-487.

对抗消化道癌症，如肝癌、肠癌、胃癌、肺癌

• Li, Guang, et al. "Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers." Journal of ethnopharmacology 153.2 (2014): 521-530.

• Lai, Wei Hong, Zamri Zainal, and Fauzi Daud. "Preliminary study on the potential of polysaccharide from indigenous Tiger's Milk mushroom (Lignosus rhinocerus) as anti-lung cancer agent." AIP Conference Proceedings. Vol. 1614. No. 1. American Institute of Physics, 2014.

抑制癌细胞增殖

• Lee, M. L., et al. "The antiproliferative activity of sclerotia of Lignosus rhinocerus (Tiger Milk Mushroom)." Evidence-based complementary and alternative medicine 2012 (2012).

增加新陈代谢，对抗糖尿病

• Yap, Hui-Yeng Y., et al. "Inhibition of protein glycation by tiger milk mushroom [Lignosus rhinocerus (Cooke) Ryvarden] and search for potential anti-diabetic activity-related metabolic pathways by genomic and transcriptomic data mining." Frontiers in pharmacology 9 (2018): 103.

辅助治疗白血病、淋巴瘤、多发性骨髓瘤、乳癌、黑色素瘤、卵巢癌、膀胱癌、前列腺癌

• Müller, Claudia I., et al. "Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells." Leukemia research 30.7 (2006): 841-848.

• Barbieri, Antonio, et al. "Anticancer and anti-inflammatory properties of Ganoderma lucidum extract effects on melanoma and triple-negative breast cancer treatment." Nutrients 9.3 (2017): 210.

• Zhao, Sufen, et al. "Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin." International journal of oncology 38.5 (2011): 1319-1327.

• Lu, Te-Ling, et al. "Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells." Food and chemical toxicology 47.8 (2009): 2013-2021.

• Zhu, T., et al. "Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells." British journal of cancer 96.4 (2007): 583-590.

保护胰岛细胞，防治糖尿病

• Jang, Jae Soon, et al. "Hispidin produced from Phellinus linteus protects pancreatic β-cells from damage by hydrogen peroxide." Archives of pharmacal research 33.6 (2010): 853-861.

调节免疫，防治过敏性皮肤炎

• Hwang, Ji Sun, et al. "Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis." BMC complementary and alternative medicine 12.1 (2012): 159.

有效治疗过敏性肺炎

• Tanaka, Hiroshi, et al. "Successful treatment of hypersensitivity pneumonitis caused by Grifola frondosa (Maitake) mushroom using a HFA-BDP extra-fine aerosol." Internal medicine 43.8 (2004): 737-740.

有益于艾滋病治疗

• Nanba, Hiroaki, et al. "Effects of maitake (Grifola frondosa) glucan in HIV-infected patients." Mycoscience 41.4 (2000): 293-295.

抗血管增生，有助于缩小肿瘤

• Lee, Jong-Suk, et al. "Grifola frondosa (maitake mushroom) water extract inhibits vascular endothelial growth factor-induced angiogenesis through inhibition of reactive oxygen species and extracellular signal-regulated kinase phosphorylation." Journal of medicinal food 11.4 (2008): 643-651.

对抗自由基

• Cui, Yong, Dong-Seok Kim, and Kyoung-Chan Park. "Antioxidant effect of Inonotus obliquus." Journal of Ethnopharmacology 96.1-2 (2005): 79-85.

改善神经衰弱症状

• Tang, Wenbo, et al. "A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia." Journal of medicinal food 8.1 (2005): 53-58.

你知道吗？

巴西圣保罗郊外有一个名叫“皮耶达提(Piedade)”的长寿村，平均年龄高达95岁以上，而且疾病罹患率很低，几乎没有人患癌症。他们的长寿秘诀，就是天天吃巴西蘑菇。

Q&A

什么是“生物反应调节剂”？

生物反应调节剂具有多种功能和用途。它可以诱导肿瘤细胞回转变成正常细胞；增强身体对抗毒素的耐受力和防御力；减少放化疗副作用；还能治疗各种病毒性感染如肝炎、艾滋病等，并促使病人早日康复。